Bukayo Saka, 23, was substituted out of the game in the 53rd minute after feeling a hamstring strain while sprinting with a defender.
Martin Odegaard, 26, left the field in the 38th minute due to a suspected shoulder problem, replaced by young Ethan Nwaneri.
Despite the setbacks, Arsenal's strong team performance ensured a convincing win, propelling the North London club to the top of the Premier League table.
Speaking to the press after the game, Arteta expressed concern for the two injured players, stating that they will undergo further evaluation, including scans, to determine the extent of their injuries.
Arteta emphasized the importance of having a large and deep squad to compensate for the losses of key players, such as Kai and now Saka and Odegaard.