Manchester United manager Ruben Amorim has decided to start new goalkeeper Altay Bayindir, while Andre Onana is left out of the matchday squad. Benjamin Sesko, a new signing, will start on the bench.
Arsenal boss Mikel Arteta has chosen Viktor Gyokeres to lead the attack, with Martin Zubimendi making his debut in midfield.
The Manchester United line-up is: Bayindir, De Light, Yoro, Shaw, Dalot, Fernandes, Casemiro, Dorgu, Mount, Mbeumo, and Cunha. The substitutes are Heaton, Maguire, Zirkzee, Amad, Ugarte, Heaven, Sesko, Fredricson, and Mainoo.
The Arsenal line-up is: Raya, White, Saliba, Gabriel, Calafiori, Zubimendi, Rice, Odegaard, Martinelli, Saka, and Gyokeres. The substitutes are Arrizabalaga, Mosquera, Merino, Nwaneri, Madueke, Havertz, Lewis-Skelly, Timber, and Trossard.